Publications

*Selected recent publications are shown below; click HERE for our full publication list

Vaccine and Immunity

Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

Wenxi Xu, Laura M Snell, Mengdi Guo, Giselle Boukhaled, Bethany L Macleod, Ming Li, Michael V Tullius, Cynthia J Guidos, Ming-Sound Tsao, Maziar Divangahi, Marcus A Horwitz, Jun Liu, David G Brooks
Immunity, 2021
 

Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2

Huibi Cao, Juntao Mai, Zhichang Zhou, Zhijie Li, Rongqi Duan, Jacqueline Watt, Ziyan Chen, Ranmal Avinash Bandara, Ming Li, Sang Kyun Ahn, Betty Poon, Natasha Christie-Holmes, Scott D Gray-Owen, Arinjay Banerjee, Karen Mossman, Rob Kozak, Samira Mubareka, James M Rini, Jim Hu, Jun Liu

Cell & Bioscience, 2021

 

Preclinical Progress of Subunit and Live Attenuated Mycobacterium tuberculosis Vaccines: A Review following the First in Human Efficacy Trial

 Jacqueline Watt, Jun Liu

Pharmaceutics, 2020

 

Recombinant BCG overexpressing phoP-phoR confers enhanced protection against tuberculosis

Sang Kyun Ahn, Vanessa Tran, Andrea Leung, Mark Ng, Ming Li, Jun Liu

Molecular Therapy, 2018

 

Loss of lipid virulence factors reduces the efficacy of the BCG vaccine

Vanessa Tran, Sang Kyun Ahn, Mark Ng, Ming Li, Jun Liu

Scientific Reports, 2016

 

Variable virulence and efficacy of BCG vaccine strains in mice and correlation with genome polymorphisms

Lu Zhang, Huan-wei Ru, Fu-zeng Chen, Chun-yan Jin, Rui-feng Sun, Xiao-yong Fan, Ming Guo, Jun-tao Mai, Wen-xi Xu, Qing-xia Lin, Jun Liu

Molecular Therapy, 2016

 

Small RNA and Transcription Factor

Mycobacterium tuberculosis 6C sRNA binds multiple mRNA targets via C-rich loops independent of RNA chaperones

Juntao Mai, Chitong Rao, Jacqueline Watt, Xian Sun, Chen Lin, Lu Zhang, Jun Liu

Nucleic Acids Research, 2019

 

Xenogeneic silencing and bacterial genome evolution: mechanisms for DNA recognition imply multifaceted roles of xenogeneic silencers

Bo Duan, Pengfei Ding, William Wiley Navarre, Jun Liu, Bin Xia

Molecular Biology and Evolution, 2021

 

Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins

Blair RG Gordon, Yifei Li, Atina Cote, Matthew T Weirauch, Pengfei Ding, Timothy R Hughes, William Wiley Navarre, Bin Xia, Jun Liu

Proceedings of the National Academy of Sciences, 2011

 

Lsr2 is a nucleoid-associated protein that targets AT-rich sequences and virulence genes in Mycobacterium tuberculosis

Blair RG Gordon, Yifei Li, Linru Wang, Anna Sintsova, Harm Van Bakel, Songhai Tian, William Wiley Navarre, Bin Xia, Jun Liu

Proceedings of the National Academy of Sciences, 2010

Drug and Target

Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline

Hui Guo, Gautier M Courbon, Stephanie A Bueler, Juntao Mai, Jun Liu, John L Rubinstein

Nature, 2021

 

Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide

Juanjuan Yang, Yindi Liu, Jing Bi, Qixu Cai, Xinli Liao, Wenqian Li, Chenyun Guo, Qian Zhang, Tianwei Lin, Yufen Zhao, Honghai Wang, Jun Liu, Xuelian Zhang, Donghai Lin

Molecular Microbiology, 2015

Updated on September 2023